What does the term “inversion” refer to when processing blood specimens?

The term "inversion" refers to the gentle mixing of blood with the anticoagulant by inverting the tube several times. This step is crucial in the specimen processing workflow because it ensures that the anticoagulant thoroughly mixes with the blood sample to prevent clotting. When blood is drawn into a collection tube containing an anticoagulant, simply allowing the tube to sit may lead to the formation of clots, which can invalidate test results. By inverting the tube, a proper mix is created, allowing the anticoagulant to work effectively, ensuring accurate laboratory analysis. Proper inversion techniques typically involve turning the tube upside down and back right side up several times, as specified by manufacturer guidelines or standard operating procedures.